Showing chemical card for P1,P4-bis(5'-guanosyl) tetraphosphate (CFc000337935)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:32:04 UTC
Chemfont ID
CFc000337935
Molecule Identification
Common Name
P1,P4-bis(5'-guanosyl) tetraphosphate
Definition
P(1),p(4)-bis(5'-guanosyl) tetraphosphate, also known as gp4g or gppppg, is a member of the class of compounds known as (5'->5')-dinucleotides (5'->5')-dinucleotides are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage. P(1),p(4)-bis(5'-guanosyl) tetraphosphate is soluble (in water) and an extremely strong acidic compound (based on its pKa). P(1),p(4)-bis(5'-guanosyl) tetraphosphate can be found in a number of food items such as allium (onion), pasta, rocket salad (sspecies), and vanilla, which makes p(1),p(4)-bis(5'-guanosyl) tetraphosphate a potential biomarker for the consumption of these food products. P(1),p(4)-bis(5'-guanosyl) tetraphosphate exists in all living species, ranging from bacteria to humans. In humans, p(1),p(4)-bis(5'-guanosyl) tetraphosphate is involved in few metabolic pathways, which include azathioprine action pathway, mercaptopurine action pathway, purine metabolism, and thioguanine action pathway. P(1),p(4)-bis(5'-guanosyl) tetraphosphate is also involved in several metabolic disorders, some of which include lesch-nyhan syndrome (LNS), myoadenylate deaminase deficiency, mitochondrial DNA depletion syndrome, and xanthine dehydrogenase deficiency (xanthinuria).
Belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
