| Definition | 1,2-dihydroxybenzene, also known as pyrocatechol or 2-hydroxyphenol, is a member of the class of compounds known as catechols. Catechols are compounds containing a 1,2-benzenediol moiety. 1,2-dihydroxybenzene is soluble (in water) and a very weakly acidic compound (based on its pKa). 1,2-dihydroxybenzene can be found in a number of food items such as orange bell pepper, squashberry, cauliflower, and allspice, which makes 1,2-dihydroxybenzene a potential biomarker for the consumption of these food products. 1,2-dihydroxybenzene can be found primarily in blood, feces, saliva, and urine, as well as throughout most human tissues. 1,2-dihydroxybenzene exists in all living organisms, ranging from bacteria to humans. In humans, 1,2-dihydroxybenzene is involved in a couple of metabolic pathways, which include disulfiram action pathway and tyrosine metabolism. 1,2-dihydroxybenzene is also involved in several metabolic disorders, some of which include hawkinsinuria, tyrosinemia type I, dopamine beta-hydroxylase deficiency, and monoamine oxidase-a deficiency (MAO-A). Moreover, 1,2-dihydroxybenzene is found to be associated with schizophrenia. 1,2-dihydroxybenzene is formally rated as possibly a carcinogenic (IARC 2B) potentially toxic compound. |
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| 1,2-Benzenediol | ChEBI | | 1,2-Dihydroxybenzene | ChEBI | | 2-Hydroxyphenol | ChEBI | | alpha-Hydroxyphenol | ChEBI | | Brenzcatechin | ChEBI | | O-Benzenediol | ChEBI | | O-Hydroxyphenol | ChEBI | | Pyrocatechin | ChEBI | | a-Hydroxyphenol | Generator | | Α-hydroxyphenol | Generator | | Catechol | HMDB | | Durafur developer C | HMDB | | Fouramine PCH | HMDB | | Fourrine 68 | HMDB | | O-Dihydroxybenzene | HMDB | | O-Dioxybenzene | HMDB | | O-Hydroquinone | HMDB | | O-Phenylenediol | HMDB | | Oxyphenate | HMDB | | Oxyphenic acid | HMDB | | Pelagol grey C | HMDB | | Phthalhydroquinone | HMDB | | Phthalic alcohol | HMDB | | Pyrocatechine | HMDB | | 1,3-Dihydroxybenzene | HMDB | | Catechol dipotassium salt | HMDB | | Catechol, 14C-labeled CPD | HMDB | | Catechol sodium salt | HMDB | | Benzene-1,2-diol | PhytoBank | | Pyrocatechol | PhytoBank | | 1,2-Hydroxybenzene | PhytoBank |
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