Showing chemical card for 3-methoxy-4-hydroxyphenylglycol (CFc000337584)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:31:27 UTC
Chemfont ID
CFc000337584
Molecule Identification
Common Name
3-methoxy-4-hydroxyphenylglycol
Definition
Vanylglycol, also known as methoxyhydroxyphenylglycol or 4-hydroxy-3-methoxy-B-phenylglycol, is a member of the class of compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Vanylglycol is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Vanylglycol can be found in a number of food items such as common bean, arrowroot, tree fern, and garland chrysanthemum, which makes vanylglycol a potential biomarker for the consumption of these food products. Vanylglycol can be found primarily in blood, cerebrospinal fluid (CSF), and urine, as well as throughout most human tissues. In humans, vanylglycol is involved in a couple of metabolic pathways, which include disulfiram action pathway and tyrosine metabolism. Vanylglycol is also involved in several metabolic disorders, some of which include hawkinsinuria, tyrosinemia type I, tyrosinemia, transient, of the newborn, and dopamine beta-hydroxylase deficiency. Moreover, vanylglycol is found to be associated with hereditary spastic paraplegia, major depressive disorder, olivopontocerebral atrophy, and sepiapterin reductase deficiency.
Belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety.
